Search Lake City hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Lake City hotels

The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.4 out of 10, Exceptional, (828)
"Awesome hotel stay "
United States
Jerry
The price is AU$222
includes taxes & fees
19 Dec - 20 Dec
The Inn at the Crossroads

Quality Inn & Suites Lake City

Quality Inn & Suites Lake City
2.5 star property
Lake City
7.0 out of 10, Good, (166)
"Good for the weekend. "
United States
Amber
The price is AU$161
includes taxes & fees
6 Jan - 7 Jan 2026
Quality Inn & Suites Lake City

Days Inn by Wyndham Lake City

Days Inn by Wyndham Lake City
2.0 star property
Lake City
6.4 out of 10, (241)
"Overall good stay for 1 night. "
United States
April
The price is AU$165
includes taxes & fees
4 Jan - 5 Jan 2026
Days Inn by Wyndham Lake City

Security inn & suites

Security inn & suites
2.0 star property
Lake City
The price is AU$182
includes taxes & fees
1 Jan - 2 Jan 2026
Security inn & suites

Bella's Boutique Hotel

Bella's Boutique Hotel
2.0 star property
Hemingway
6.0 out of 10, (12)
"Quaint and cozy, convenient for visiting family. The staff and owner were very welcoming and generous. "
United States
James
The price is AU$149
includes taxes & fees
18 Dec - 19 Dec
Bella's Boutique Hotel

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (702)
"Good stay, great staff"
United States
James
The price is AU$168
includes taxes & fees
21 Dec - 22 Dec
TownePlace Suites by Marriott Florence

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1169)
"Enjoyed our stay there. "
United States
Cathy
The price is AU$164
includes taxes & fees
30 Dec - 31 Dec
Comfort Inn & Suites Florence Center Area

Courtyard by Marriott Florence

Courtyard by Marriott Florence
3.0 star property
Florence
7.8 out of 10, Good, (700)
"Great hotel! Great front desk staff! Great stay!"
United States
William
The price is AU$163
includes taxes & fees
1 Jan - 2 Jan 2026
Courtyard by Marriott Florence

Aloft Florence

Aloft Florence
3.0 star property
Florence
8.6 out of 10, Excellent, (249)
"You have to try the apple muffin. It’s so delicious my whole family had to try it. "
United States
Tyler
The price is AU$170
includes taxes & fees
21 Dec - 22 Dec
Aloft Florence

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1000)
"Very good breakfast & convenient location"
United States
Diedre
The price is AU$186
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
2.5 star property
Florence
9.0 out of 10, Wonderful, (553)
"Clean room, professional and courteous staff. "
United States
Felicia
The price is AU$174
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites by Marriott Florence I-20

SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
Florence
8.6 out of 10, Excellent, (967)
"Easy check-in. Nice room. "
United States
Tim
The price is AU$182
includes taxes & fees
21 Dec - 22 Dec
SpringHill Suites by Marriott Florence

Hilton Garden Inn Florence

Hilton Garden Inn Florence
2.5 star property
Florence
8.6 out of 10, Excellent, (253)
"Restaurants, shopping (the Mall) was right across the street. Stay was very friendly and helpful."
United States
Janie
The price is AU$167
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Florence

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (926)
"Friendly staff, great breakfast, beautiful ammenities!"
United States
Brandi
The price is AU$211
includes taxes & fees
11 Jan - 12 Jan 2026
Staybridge Suites Florence - Civic Center by IHG

Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence
3.0 star property
Florence
8.4 out of 10, Very good, (657)
"The staff was amazing and the hotel is pretty fresh in terms of amenities "
United States
Shahid
The price is AU$170
includes taxes & fees
11 Jan - 12 Jan 2026
Homewood Suites by Hilton Florence

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (819)
"My go to stay while in Fairfax. "
United States
Gregory
The price is AU$165
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Florence Center

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
6.8 out of 10, (1001)
"Staff was friendly and the hotel was easy access to I95 which made it stress free. Room was clean and the Heat worked! "
United States
Robert Patrick
The price is AU$108
includes taxes & fees
22 Dec - 23 Dec
Days Inn by Wyndham Florence Near Civic Center

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
3.0 star property
Florence
8.2 out of 10, Very good, (1001)
"Clean room, good location, quick checkin"
United States
Brian
The price is AU$179
includes taxes & fees
11 Jan - 12 Jan 2026
Home2 Suites by Hilton Florence, SC

Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
Florence
8.8 out of 10, Excellent, (478)
"Yes our stay was great big variety on breakfast clean hotel rooms nice to have a kitchen had a great day"
United States
Marialinda
The price is AU$161
includes taxes & fees
25 Dec - 26 Dec
Residence Inn Marriott Florence

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1252)
"Newly remodeled rooms. Very clean. Very friendly staff "
United States
Theresa
The price is AU$131
includes taxes & fees
15 Jan - 16 Jan 2026
Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Lake City attractions

Learn more about Lake City

Stroll through Moore Farms Botanical Garden's lush landscapes, where seasonal blooms and tranquil paths await. Dive into local history at the Bean Market, a restored 1930s tobacco warehouse now hosting community events and showcasing regional culture.

a stunning aerial panoramic shot of the blue waters of Lake Hartwell surrounded by vast miles of lush green trees and grass with powerful clouds at sunset in Fair Play South Carolina USA

Top Lake City Hotel Reviews

Recent Reviews in Lake City

More cheap accommodation in Lake City

Frequently asked questions

What's the best place for a stay in Lake City?
The Inn at the Crossroads is a favourite with Expedia customers. This hotel offers free breakfast and a restaurant. Quality Inn & Suites Lake City is another favourite option for your trip based on traveller reviews. See all available top hotels, or vacation rentals in Lake City.
What are some of the best holiday rentals that Lake City has to offer?
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's: This holiday home rental outside of Lake City offers a fireplace, a patio and air conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of garden in this rental home to help you unwind. See all vacation rentals in Lake City.
If I need to cancel my hotel reservation in Lake City, will I receive a refund?
Yes, most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Lake City.
What is the top LGBTQ-friendly accommodation in Lake City?
The Inn at the Crossroads is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. See all available hotels listed as LGBTQ-friendly in Lake City.
What is staying in Lake City like?
Visitors to Lake City will definitely enjoy the lakeside setting and restaurants. Tourists can also enjoy the city's shopping and parks. In Lake City, there are 4 hotels and other accommodation options to choose from. Find out more about Lake City.
What is there to see in Lake City?
Natural beauty is on display at Lions Park, Ronald E. McNair Life History Center and Moore Farms Botanical Garden. A couple of additional sights to add to your itinerary are The Country Club at Lake City and Lynches Lake Historical Society. Take a look at what more there is to see and do in Expedia's Lake City guide.
What's the weather like in Lake City?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Lake City is 1354 mm.

Explore a world of travel with Expedia